SCHEMBL7080156

SCHEMBL7080156

O=C(N(F)F)C(F)(C(=S)N(F)F)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.37
ALDH1A1 P00352 2/20 0.35
TSHR P16473 2/20 0.35
CES1 P23141 2/20 0.34
CYP1A2 P05177 1/20 0.34
OPRM1 P35372 2/20 0.33
DRD3 P35462 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
HTT P42858 2/20 0.33
MEN1 O00255 1/20 0.33
RAB9A P51151 1/20 0.33
DRD2 P14416 1/20 0.33
DRD4 P21917 1/20 0.33
KCNN4 O15554 3/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA5A P35218 1/20 0.32
CA9 Q16790 1/20 0.32
PGK1 P00558 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6830148 0.87 PTPN1 (0.43) PTPN1ALDH1A1TSHRCES1CYP1A2
SCHEMBL6682057 0.87 ALDH1A1 (0.42) PTPN1ALDH1A1TSHRCES1CYP1A2
SCHEMBL9052913 0.72 KMT2A (0.44) PTPN1ALDH1A1TSHRCES1CYP1A2
SCHEMBL5012102 0.68 CYP1A2 (0.50) PTPN1ALDH1A1TSHRCES1CYP1A2
Water SCHEMBL9562304 0.68 CYP1A2 (0.50) PTPN1ALDH1A1TSHRCES1CYP1A2
SCHEMBL4245525 0.66 MAPT (0.56) PTPN1ALDH1A1TSHRCES1CYP1A2
Potassium Ion SCHEMBL5012104 0.65 PTPN1 (0.45) PTPN1ALDH1A1TSHRCES1CYP1A2
SCHEMBL3629687 0.63 CYP1A2 (0.50) PTPN1ALDH1A1TSHRCES1CYP1A2
SCHEMBL29287593 0.63 CYP1A2 (0.45) PTPN1ALDH1A1TSHRCES1CYP1A2
SCHEMBL16158180 0.62 OPRM1 (0.51) PTPN1ALDH1A1TSHROPRM1DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed