SCHEMBL7080192

SCHEMBL7080192

CC(C)(C)OC(=O)ON1CCC(c2ccc(CCOC(c3ccccc3)(c3ccccc3)c3ccccc3)nc2)C(OCc2ccc3ccccc3c2)C1

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
REN P00797 18/20 0.40
CHRM3 P20309 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7081088 0.91 REN (0.43) RENCHRM3
SCHEMBL7080928 0.90 REN (0.48) REN
SCHEMBL7082788 0.89 REN (0.40) REN
SCHEMBL7079686 0.89 REN (0.42) REN
SCHEMBL7082345 0.88 REN (0.49) REN
SCHEMBL7078204 0.87 REN (0.46) RENCHRM3
SCHEMBL6042051 0.86 REN (0.42) REN
SCHEMBL7079956 0.84 SLC6A1 (0.35)
SCHEMBL7082058 0.83 REN (0.48) REN
SCHEMBL7083199 0.83 REN (0.46) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0863875-B1 NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY HOFFMANN LA ROCHE (CH) 2003-06-04 EP disclosed