Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7080211 | 1.00 | TAS1R3 (0.38) | TAS1R3TAS1R1TAS1R2MAPTGAA | |
| SCHEMBL7082744 | 0.99 | TAS1R3 (0.39) | TAS1R3TAS1R1TAS1R2MAPTGAA | |
| SCHEMBL7082739 | 0.99 | TAS1R3 (0.39) | TAS1R3TAS1R1TAS1R2MAPTGAA | |
| SCHEMBL7082747 | 0.98 | TAS1R3 (0.35) | TAS1R3TAS1R1TAS1R2MAPTGAA | |
| SCHEMBL7082742 | 0.98 | TAS1R3 (0.35) | TAS1R3TAS1R1TAS1R2MAPTGAA | |
| SCHEMBL7083137 | 0.96 | MAPT (0.36) | TAS1R3TAS1R1TAS1R2MAPTLMNA | |
| SCHEMBL7083139 | 0.96 | MAPT (0.36) | TAS1R3TAS1R1TAS1R2MAPTLMNA | |
| SCHEMBL7079154 | 0.93 | TAS1R3 (0.36) | TAS1R3TAS1R1TAS1R2MAPTGAA | |
| SCHEMBL7079151 | 0.93 | TAS1R3 (0.36) | TAS1R3TAS1R1TAS1R2MAPTGAA | |
| SCHEMBL7083518 | 0.92 | TAS1R3 (0.37) | TAS1R3TAS1R1TAS1R2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1132375-B1 | AMINOACRYLIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | ASAHI GLASS CO LTD (JP) | 2003-07-16 | — | — | EP | disclosed |
| US-6531624-B1 | Intermediates of quinolone antibiotics;3-dimethylamino-2-(2,4,5-trifluoro-3-methyl-6 -nitrobenzoyl)acrylates | ASAHI GLASS COMPANY LTD. (JP) | 2003-03-11 | — | — | US | disclosed |
| EP-1132375-A1 | AMINOACRYLIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | ASAHI GLASS COMPANY LTD. (JP) | 2001-09-12 | — | — | EP | disclosed |