Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7083139 | 1.00 | MAPT (0.36) | MAPTLMNAGLO1CYP1A2CYP2C19 | |
| SCHEMBL7082747 | 0.96 | TAS1R3 (0.35) | MAPTLMNAGLO1CYP1A2CYP2C19 | |
| SCHEMBL7082742 | 0.96 | TAS1R3 (0.35) | MAPTLMNAGLO1CYP1A2CYP2C19 | |
| SCHEMBL7080209 | 0.96 | TAS1R3 (0.38) | MAPTLMNAGLO1CYP1A2CYP2C19 | |
| SCHEMBL7080211 | 0.96 | TAS1R3 (0.38) | MAPTLMNAGLO1CYP1A2CYP2C19 | |
| SCHEMBL7082739 | 0.95 | TAS1R3 (0.39) | MAPTLMNAGLO1TAS1R3TAS1R1 | |
| SCHEMBL7082744 | 0.95 | TAS1R3 (0.39) | MAPTLMNAGLO1TAS1R3TAS1R1 | |
| SCHEMBL7086209 | 0.93 | MAPT (0.30) | MAPTTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7086207 | 0.93 | MAPT (0.30) | MAPTTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7083859 | 0.91 | ESR1 (0.31) | MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1132375-B1 | AMINOACRYLIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | ASAHI GLASS CO LTD (JP) | 2003-07-16 | — | — | EP | disclosed |
| US-6531624-B1 | Intermediates of quinolone antibiotics;3-dimethylamino-2-(2,4,5-trifluoro-3-methyl-6 -nitrobenzoyl)acrylates | ASAHI GLASS COMPANY LTD. (JP) | 2003-03-11 | — | — | US | disclosed |
| EP-1132375-A1 | AMINOACRYLIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | ASAHI GLASS COMPANY LTD. (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5859026-A | ADMINISTERING AS AN ANTIBACTERIAL AGENT | HOKURIKU SEIYAKU CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0806421-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-11-12 | — | — | EP | disclosed |
| EP-0641793-B1 | 5-Amino-8-methyl-7-pyrrolidinylquinoline-3-carboxylic acid derivative | HOKURIKU PHARMACEUTICAL (JP) | 1996-10-23 | — | — | EP | disclosed |
| US-5547962-A | QUINOLONE ANTIBIOTICS | HORURIKU SEIYAKU CO., LTD. (JP) | 1996-08-20 | — | — | US | disclosed |
| EP-0641793-A1 | 5-Amino-8-methyl-7-pyrrolidinylquinoline-3-carboxylic acid derivative | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |