Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5531847 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2CHRNA7EDNRAMEN1KMT2A | |
| SCHEMBL3009817 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2CHRNA7EDNRAMEN1KMT2A | |
| SCHEMBL29543300 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2CHRNA7EDNRAMEN1KMT2A | |
| SCHEMBL6769226 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2CHRNA7EDNRAMEN1KMT2A | |
| SCHEMBL6769452 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2CHRNA7EDNRAMEN1KMT2A | |
| SCHEMBL8700809 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2CHRNA7EDNRAMEN1KMT2A | |
| SCHEMBL7385475 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2CHRNA7EDNRAMEN1KMT2A | |
| SCHEMBL10537566 | 0.77 | SMN1; SMN2 (0.61) | SMN1; SMN2CHRNA7MEN1KMT2AGBA1 | |
| SCHEMBL30943497 | 0.77 | SMN1; SMN2 (0.61) | SMN1; SMN2CHRNA7MEN1KMT2AGBA1 | |
| SCHEMBL31146730 | 0.77 | SMN1; SMN2 (0.61) | SMN1; SMN2CHRNA7MEN1KMT2AGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3896058-A2 | ENANTIONSELECTIVE PROCESSES TO INSECTICIDAL 3-ARYL-3-TRIFLUOROMETHYL-SUBSTITUTED PYRROLIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-10-20 | — | — | EP | disclosed |
| EP-2763963-B1 | ENANTIONSELECTIVE PROCESSES TO INSECTICIDAL 3-ARYL-3-TRIFLUOROMETHYL-SUBSTITUTED PYRROLIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-05-26 | — | — | EP | disclosed |
| US-9469633-B2 | Processes for the preparation of pyrrolidine intermediates | SYNGENTA PARTICIPATIONS AG (CH) | 2016-10-18 | — | — | US | disclosed |
| US-20140296527-A1 | PROCESSES FOR THE PREPARATION OF PYRROLIDINE INTERMEDIATES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-02 | — | — | US | disclosed |
| US-20070276142-A1 | Catalytic Asymmetric Synthesis of Optically Active Alpha-Halo-Carbonyl Compounds | CHEMINOVA A/S (DK) | 2007-11-29 | — | — | US | disclosed |
| US-20070276142-A1 | Catalytic Asymmetric Synthesis of Optically Active Alpha-Halo-Carbonyl Compounds | CHEMINOVA A/S (DK) | 2007-11-29 | — | — | US | disclosed |
| WO-2003050105-A2 | CATALYTIC ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS | CHEMINOVA A/S (DK) | 2003-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276142-A1 | Catalytic Asymmetric Synthesis of Optically Active Alpha-Halo-Carbonyl Compounds | CBR1, CBR3, HAO1 | SMN1; SMN2 4050/4885CHRNA7 1564/4885EDNRA 3029/4885 |
| US-20140296527-A1 | PROCESSES FOR THE PREPARATION OF PYRROLIDINE INTERMEDIATES | PPOX, PRDX2, CBR1 | SMN1; SMN2 3044/4885CHRNA7 3458/4885EDNRA 2086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.