Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8175837 | 1.00 | TSHR (0.37) | TSHRMAPTLMNAKMT2AMEN1 | |
| SCHEMBL7081782 | 0.84 | ALDH1A1 (0.36) | TSHRMAPTLMNAKMT2AMEN1 | |
| SCHEMBL7168941 | 0.84 | ALDH1A1 (0.36) | TSHRMAPTLMNAKMT2AMEN1 | |
| SCHEMBL16164369 | 0.84 | ALDH1A1 (0.40) | TSHRMAPTLMNAKMT2AMEN1 | |
| SCHEMBL14921076 | 0.84 | ALDH1A1 (0.40) | TSHRMAPTLMNAKMT2AMEN1 | |
| SCHEMBL7177098 | 0.82 | TSHR (0.37) | TSHRMAPTLMNAKMT2AMEN1 | |
| SCHEMBL7177101 | 0.82 | TSHR (0.37) | TSHRMAPTLMNAKMT2AMEN1 | |
| SCHEMBL14920852 | 0.81 | KDM4A (0.34) | TSHRMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL16163859 | 0.81 | KDM4A (0.34) | TSHRMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL7077658 | 0.76 | SMN1; SMN2 (0.35) | TSHRMAPTLMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0960100-B1 | SUBSTITUTED 4-BENZOYL-PYRAZOLES | BASF AG (DE) | 2003-07-09 | — | — | EP | disclosed |
| US-6028035-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-02-22 | — | — | US | disclosed |