Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7077661 | 1.00 | SMN1; SMN2 (0.35) | SMN1; SMN2RAB9AKMT2AALDH1A1TSHR | |
| Ethanesulfonic Acid Amide SCHEMBL3436960 | 0.76 | ALDH1A1 (0.37) | SMN1; SMN2RAB9AKMT2AALDH1A1TSHR | |
| SCHEMBL8175837 | 0.76 | TSHR (0.37) | SMN1; SMN2KMT2AALDH1A1TSHRLMNA | |
| SCHEMBL7080277 | 0.76 | TSHR (0.37) | SMN1; SMN2KMT2AALDH1A1TSHRLMNA | |
| SCHEMBL9076246 | 0.75 | SMN1; SMN2 (0.38) | SMN1; SMN2RAB9AKMT2AALDH1A1TSHR | |
| SCHEMBL4245180 | 0.75 | RAB9A (0.38) | SMN1; SMN2RAB9AKMT2AALDH1A1TSHR | |
| SCHEMBL9076935 | 0.75 | SMN1; SMN2 (0.40) | SMN1; SMN2RAB9AKMT2AALDH1A1TSHR | |
| SCHEMBL6584802 | 0.75 | RAB9A (0.33) | SMN1; SMN2RAB9AKMT2AALDH1A1TSHR | |
| SCHEMBL3436915 | 0.73 | RAB9A (0.36) | SMN1; SMN2RAB9AKMT2AALDH1A1TSHR | |
| SCHEMBL27524777 | 0.72 | LMNA (0.44) | SMN1; SMN2RAB9AKMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0960100-B1 | SUBSTITUTED 4-BENZOYL-PYRAZOLES | BASF AG (DE) | 2003-07-09 | — | — | EP | disclosed |
| US-6028035-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-02-22 | — | — | US | disclosed |