SCHEMBL7080313

SCHEMBL7080313

COCCP(CCOC)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.38
MAPK1 P28482 2/20 0.38
HPGD P15428 3/20 0.37
TDP1 Q9NUW8 2/20 0.36
CYP3A4 P08684 1/20 0.36
RAB9A P51151 1/20 0.36
TSHR P16473 2/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
KCNH3 Q9ULD8 1/20 0.33
CA4 P22748 1/20 0.33
ADRB2 P07550 1/20 0.33
MAPT P10636 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
ALDH1A1 P00352 2/20 0.32
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7517627 0.86 GLA (0.32) CA2MAPK1HPGDRAB9ATSHR
SCHEMBL6057042 0.82 CA2 (0.38) CA2MAPK1HPGDTDP1CYP3A4
Bromide SCHEMBL28416675 0.80 CA2 (0.37) CA2MAPK1HPGDTDP1CYP3A4
SCHEMBL12313465 0.78 ALDH1A1 (0.32) CA2RAB9AMEN1KMT2AALDH1A1
SCHEMBL26926174 0.76 CYP3A4 (0.60) CA2MAPK1HPGDTDP1CYP3A4
SCHEMBL12313427 0.75 MAPK1 (0.35) CA2MAPK1HPGDTDP1RAB9A
SCHEMBL28079758 0.74 CYP3A4 (0.57) CA2MAPK1HPGDTDP1CYP3A4
SCHEMBL15417419 0.74 MAPK1 (0.40) CA2MAPK1HPGDTDP1CYP3A4
SCHEMBL11758266 0.74 ALDH1A1 (0.48) HPGDTDP1RAB9AMAPTALDH1A1
SCHEMBL8835943 0.73 CYP3A4 (0.41) MAPK1HPGDTDP1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1090923-B1 Process for the preparation of ruthenium hydrogenation catalysts and use thereof DU PONT (US) 2003-07-16 EP disclosed
EP-1090905-B1 Use of ruthenium hydrogenation catalysts DU PONT (US) 2002-12-18 EP disclosed
EP-1031379-B1 Catalyst comprising rutheniumcomplex, and use thereof in hydrogenation of unsaturated substrates, especially organic nitriles DU PONT (US) 2002-10-23 EP disclosed
EP-1172691-A1 Method of processing photographic silver-dye-bleach materials and bleaching solution preparations therefor ILFORD Imaging Switzerland GmbH (CH) 2002-01-16 EP disclosed
EP-0839150-B1 PROCESS FOR THE PREPARATION OF RUTHENIUM HYDROGENATION CATALYSTS AND PRODUCTS THEREOF DU PONT (US) 2001-12-05 EP disclosed
EP-0807119-B1 PROCESS FOR THE PREPARATION OF RUTHENIUM COMPLEXES AND THEIR IN SITU USE AS HYDROGENATION CATALYSTS DU PONT (US) 2001-07-18 EP disclosed
EP-1090905-A1 Process for the preparation of ruthenium hydrogenation catalysts and products thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-04-11 EP disclosed
EP-1090923-A1 Process for the preparation of ruthenium hydrogenation catalysts and products thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-04-11 EP disclosed
EP-1031379-A1 Catalyst comprising rutheniumcomplex, and use thereof in hydrogenation of unsaturated substrates, especially organic nitriles E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-08-30 EP disclosed
EP-0807098-B1 IMPROVED PROCESS FOR REDUCTIVE HYDROLYSIS OF NITRILES DU PONT (US) 1998-09-09 EP disclosed
EP-0014688-B1 PROCESS FOR THE TREATMENT OF SILVER DYE-BLEACHING MATERIALS, AQUEOUS PREPARATION THEREFOR, CONCENTRATE AND PROCESS FOR MAKING THE PREPARATION CIBA-GEIGY AG (CH) 1983-03-23 EP disclosed
US-4366232-A Method for processing photographic silver dye-bleach materials and suitable preparations CIBA-GEIGY LTD. (CH) 1982-12-28 US disclosed
US-4357280-A Use of tertiary phosphines in photographic silver dye bleach materials CIBA-GEIGY AG (CH) 1982-11-02 US disclosed
EP-0059166-A1 Disazo dyestuffs and their use in colour-photographic light-sensitive materials for the silver dye bleaching process CIBA-GEIGY AG (CH) 1982-09-01 EP disclosed
US-4304846-A USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS CIBA-GEIGY AG (CH) 1981-12-08 US disclosed
EP-0040172-A2 Azo dyestuffs, methods for their preparation and their use as colouring agents in photographic materials in the silver dyestuff bleaching process, and the said photographic materials containing these azo dyestuffs CIBA-GEIGY AG (CH) 1981-11-18 EP disclosed
EP-0040171-A2 Azo dyestuffs, methods for their preparation and their use as colouring agents in the silver dyestuff bleaching process CIBA-GEIGY AG (CH) 1981-11-18 EP disclosed
EP-0039312-A1 Colour photopgraphic material for the silver-dye bleaching process, process for the production of this material and its use in the production of photographic images CIBA-GEIGY AG (CH) 1981-11-04 EP disclosed
EP-0014688-A2 Process for the treatment of silver dye-bleaching materials, aqueous preparation therefor, concentrate and process for making the preparation CIBA-GEIGY AG (CH) 1980-08-20 EP disclosed
US-4138256-A Method of processing photographic silver dye bleach materials CIBA-GEIGY AG (CH) 1979-02-06 US disclosed