Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 3/20 | 0.55 |
| ▸ | MAX | P61244 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | BCL2L1 | Q07817 | 6/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7076437 | 0.89 | MEN1 (0.56) | HDAC1HDAC8HDAC6BCL2L1MCL1 | |
| SCHEMBL7052824 | 0.87 | SMPD1 (0.62) | HDAC1HDAC8HDAC6BCL2L1MCL1 | |
| SCHEMBL7045604 | 0.86 | SMPD1 (0.61) | HDAC1HDAC8HDAC6BCL2L1MCL1 | |
| SCHEMBL7080255 | 0.86 | MAPT (0.58) | HDAC1HDAC8HDAC6BCL2L1MCL1 | |
| SCHEMBL7081910 | 0.86 | HDAC8 (0.64) | HDAC1HDAC8HDAC6BCL2L1MCL1 | |
| SCHEMBL7077931 | 0.86 | HDAC1 (0.54) | HDAC1HDAC8HDAC6BCL2L1MCL1 | |
| SCHEMBL7076910 | 0.86 | HDAC1 (0.59) | HDAC1HDAC8HDAC6BCL2L1MCL1 | |
| SCHEMBL7050463 | 0.84 | MYC (0.61) | MYCMAXAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7080770 | 0.84 | HDAC1 (0.52) | HDAC1HDAC8HDAC6BCL2L1MCL1 | |
| SCHEMBL7076463 | 0.83 | SMPD1 (0.52) | HDAC1HDAC8HDAC6BCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162818-A1 | Acylsulfonamide derivative | AJINOMOTO CO. INC. (JP) | 2003-08-28 | — | — | US | disclosed |
| US-6555584-B1 | Acetyl-coa carboxylase inhibitors | AJINOMOTO CO., INC. (JP) | 2003-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162818-A1 | Acylsulfonamide derivative | ACSS2, ACACA, FASN | MYC 1649/4885MAX 4277/4885HDAC1 271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.