Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 3/20 | 0.48 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11372077 | 0.73 | GSK3B (0.60) | FEN1GSK3BNPC1KMT2AMEN1 | |
| SCHEMBL6737897 | 0.72 | CNR2 (0.46) | FEN1ERCC5CNR2CNR1KDM4E | |
| SCHEMBL6233670 | 0.70 | MAPK1 (0.63) | FEN1ERCC5GSK3BCNR2CNR1 | |
| SCHEMBL6208525 | 0.70 | MEN1 (0.60) | NPC1GAAKMT2AMEN1KDM4E | |
| SCHEMBL11389635 | 0.68 | KDM4E (0.76) | GSK3BKMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL7073582 | 0.68 | KDM4E (0.49) | GAAKMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL13011130 | 0.68 | CNR2 (0.55) | FEN1ERCC5CNR2CNR1KDM4E | |
| SCHEMBL13011633 | 0.67 | CNR2 (0.50) | CNR2CNR1NPC1 | |
| SCHEMBL38660055 | 0.66 | GSK3B (0.71) | GSK3BKMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL20864215 | 0.65 | FEN1 (1.00) | FEN1ERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059356-A2 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2003-07-24 | — | — | WO | claimed |
| WO-2003059356-A2 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |