Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074520 | 0.89 | MEN1 (0.32) | MAPT | |
| SCHEMBL17242862 | 0.77 | — | — | |
| SCHEMBL4122574 | 0.66 | — | — | |
| SCHEMBL7080488 | 0.64 | NAALAD2 (0.35) | FAAHSMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL10603399 | 0.63 | — | — | |
| SCHEMBL23539308 | 0.61 | HPGD (0.32) | ALDH1A1 | |
| SCHEMBL7617788 | 0.61 | HPGD (0.32) | ALDH1A1 | |
| SCHEMBL2398399 | 0.61 | SMN1; SMN2 (0.39) | FAAHSMN1; SMN2SLC6A5ALDH1A1MAPT | |
| SCHEMBL5827532 | 0.61 | HPGD (0.32) | ALDH1A1 | |
| SCHEMBL17242845 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758328-B1 | ANTI-CANCER COMPOUNDS CONTAINING CYCLOPENTAQUINAZOLINE RING | BTG INT LTD (GB) | 2003-07-16 | — | — | EP | disclosed |