Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.33 |
| ▸ | LTA4H | P09960 | 3/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ECE1 | P42892 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074528 | 0.89 | MEN1 (0.36) | NAALAD2KMT2AALDH1A1MAPT | |
| SCHEMBL12145025 | 0.74 | GABRP (0.39) | NAALAD2CYP1A2FOLH1ANPEP | |
| SCHEMBL13840852 | 0.73 | NAALAD2 (0.42) | NAALAD2CYP1A2FOLH1 | |
| SCHEMBL14102937 | 0.70 | NAALAD2 (0.57) | NAALAD2FOLH1 | |
| SCHEMBL17242795 | 0.69 | CYSLTR2 (0.36) | KMT2AALDH1A1 | |
| SCHEMBL6954475 | 0.69 | NAALAD2 (0.43) | NAALAD2FOLH1 | |
| SCHEMBL17242863 | 0.68 | GABRP (0.34) | NAALAD2CYP1A2 | |
| SCHEMBL4122580 | 0.67 | APEX1 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL6948576 | 0.67 | GABRP (0.39) | NAALAD2CYP1A2KMT2AMAPTFOLH1 | |
| SCHEMBL4572566 | 0.66 | ALDH1A1 (0.51) | FAAHCYP1A2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758328-B1 | ANTI-CANCER COMPOUNDS CONTAINING CYCLOPENTAQUINAZOLINE RING | BTG INT LTD (GB) | 2003-07-16 | — | — | EP | disclosed |