Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7080481 | 0.89 | FAAH (0.33) | MAPT | |
| SCHEMBL17242862 | 0.74 | — | — | |
| SCHEMBL7074528 | 0.67 | MEN1 (0.36) | MEN1TSHRKMT2ABIRC2MAPT | |
| SCHEMBL7074523 | 0.65 | MAPT (0.32) | MAPTL3MBTL1 | |
| SCHEMBL4122574 | 0.63 | — | — | |
| SCHEMBL13203004 | 0.63 | — | — | |
| SCHEMBL2081022 | 0.62 | TSHR (0.51) | MEN1TSHRKMT2ABIRC2MAPT | |
| SCHEMBL25967050 | 0.62 | TSHR (0.51) | MEN1TSHRKMT2ABIRC2MAPT | |
| SCHEMBL10272433 | 0.62 | TSHR (0.51) | MEN1TSHRKMT2ABIRC2MAPT | |
| SCHEMBL10603399 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758328-B1 | ANTI-CANCER COMPOUNDS CONTAINING CYCLOPENTAQUINAZOLINE RING | BTG INT LTD (GB) | 2003-07-16 | — | — | EP | disclosed |