Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17686526 | 0.71 | ALDH1A1 (0.47) | MEN1KMT2ARECQLHPGDPKM | |
| SCHEMBL24018479 | 0.71 | MEN1 (0.44) | MEN1KMT2ARECQLHPGDPKM | |
| SCHEMBL6775540 | 0.71 | RECQL (0.44) | MEN1KMT2ARECQLHPGDPKM | |
| SCHEMBL3742035 | 0.71 | MEN1 (0.47) | MEN1KMT2ARECQLHPGDPKM | |
| SCHEMBL6943164 | 0.68 | PKM (0.42) | MEN1KMT2ARECQLHPGDPKM | |
| SCHEMBL5964995 | 0.68 | MEN1 (0.42) | MEN1KMT2ARECQLHPGDPKM | |
| SCHEMBL24666635 | 0.67 | MEN1 (0.41) | MEN1KMT2ARECQLHPGDPKM | |
| SCHEMBL18839851 | 0.66 | PKM (0.47) | MEN1KMT2ARECQLHPGDPKM | |
| SCHEMBL11530868 | 0.66 | PKM (0.41) | MEN1KMT2ARECQLHPGDPKM | |
| SCHEMBL6801632 | 0.64 | TDP1 (0.54) | MEN1KMT2ARECQLHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758328-B1 | ANTI-CANCER COMPOUNDS CONTAINING CYCLOPENTAQUINAZOLINE RING | BTG INT LTD (GB) | 2003-07-16 | — | — | EP | claimed |