Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | F10 | P00742 | 8/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | F9 | P00740 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | ADCY6 | O43306 | 2/20 | 0.36 |
| ▸ | ADCY3 | O60266 | 2/20 | 0.36 |
| ▸ | ADCY9 | O60503 | 2/20 | 0.36 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.36 |
| ▸ | ADCY8 | P40145 | 2/20 | 0.36 |
| ▸ | GCGR | P47871 | 2/20 | 0.36 |
| ▸ | ADCY7 | P51828 | 2/20 | 0.36 |
| ▸ | ADCY2 | Q08462 | 2/20 | 0.36 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.36 |
| ▸ | ADCY4 | Q8NFM4 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7081749 | 0.81 | F10 (0.42) | PPARGPPARAF10PRSS1F9 | |
| SCHEMBL7076322 | 0.80 | F10 (0.51) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7002197 | 0.78 | F10 (0.47) | F10PRSS1NAMPTF2KMT2A | |
| SCHEMBL7006420 | 0.78 | F10 (0.65) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7007614 | 0.78 | F10 (0.65) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7007797 | 0.78 | F10 (0.53) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6422067 | 0.78 | F10 (0.53) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6298107 | 0.78 | F10 (0.53) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7075874 | 0.77 | POLB (0.40) | F10PRSS1NAMPTF2KMT2A | |
| SCHEMBL6296860 | 0.76 | F10 (0.53) | F10PRSS1F2PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322618-A1 | AMINO HETEROCYCLIC COMPOUNDS (FACTOR X A? INHIBITORS 14) | MERCK PATENT GmbH (DE) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002024654-A1 | AMINO HETEROCYCLIC COMPOUNDS (FACTOR XA INHIBITORS 14) | MERCK PATENT GMBH (DE) | 2002-03-28 | — | — | WO | disclosed |