Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7081957 | 0.87 | ALDH1A1 (0.38) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL7081530 | 0.77 | LMNA (0.35) | — | |
| SCHEMBL7081959 | 0.77 | ALDH1A1 (0.32) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL986625 | 0.77 | ALDH1A1 (0.33) | ALDH1A1TP53 | |
| SCHEMBL1259913 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL30634536 | 0.74 | ALDH1A1 (0.42) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL10852253 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL1463974 | 0.73 | SERPINE1 (0.38) | ALDH1A1TP53 | |
| SCHEMBL14008188 | 0.73 | LMNA (0.39) | ALDH1A1TP53 | |
| SCHEMBL18293613 | 0.73 | CYP2C19 (0.33) | ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242501-B1 | POLYETHER CARBONATES | BAYER AG (DE) | 2003-09-03 | — | — | EP | claimed |
| US-20030009003-A1 | Polyether carbonates | BAYER AKTIENGESELLSCHAFT (DE) | 2003-01-09 | — | — | US | claimed |
| US-4031110-A | Method of preparing 3,3-Bis (chloromethyl) oxetane | NATIONAL PATENT DEVELOPMENT CORPORATION (US) | 1977-06-21 | — | — | US | disclosed |