Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL708156 | 1.00 | PIK3CA (0.35) | PIK3CAPRKDCPARP1 | |
| SCHEMBL705496 | 0.85 | PIK3CA (0.37) | PIK3CAPRKDCPARP1 | |
| SCHEMBL705497 | 0.85 | PIK3CA (0.37) | PIK3CAPRKDCPARP1 | |
| SCHEMBL708157 | 0.83 | SYK (0.35) | PIK3CAPRKDCPARP1 | |
| SCHEMBL703954 | 0.81 | PIK3CA (0.32) | PIK3CAPRKDCPARP1 | |
| SCHEMBL703955 | 0.81 | PIK3CA (0.32) | PIK3CAPRKDCPARP1 | |
| SCHEMBL650961 | 0.79 | MAPT (0.38) | PIK3CAPRKDC | |
| SCHEMBL650959 | 0.79 | MAPT (0.38) | PIK3CAPRKDC | |
| SCHEMBL708508 | 0.78 | UTS2R (0.32) | PIK3CAPRKDC | |
| SCHEMBL708158 | 0.77 | PIK3CA (0.31) | PIK3CAPRKDCPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423204-A1 | THIAZOLIDINONE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2012-02-29 | — | — | EP | disclosed |