Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
| ▸ | TNKS | O95271 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL703954 | 0.84 | PIK3CA (0.32) | PIK3CAPRKDCPARP1TNKSNUAK1 | |
| SCHEMBL703955 | 0.84 | PIK3CA (0.32) | PIK3CAPRKDCPARP1TNKSNUAK1 | |
| SCHEMBL705496 | 0.84 | PIK3CA (0.37) | PIK3CAPRKDCPARP1 | |
| SCHEMBL705497 | 0.84 | PIK3CA (0.37) | PIK3CAPRKDCPARP1 | |
| SCHEMBL708159 | 0.83 | PIK3CA (0.35) | PIK3CAPRKDCPARP1 | |
| SCHEMBL708156 | 0.83 | PIK3CA (0.35) | PIK3CAPRKDCPARP1 | |
| SCHEMBL655203 | 0.82 | PARP1 (0.34) | PARP1ALDH1A1 | |
| SCHEMBL702258 | 0.79 | SETD1B (0.33) | — | |
| SCHEMBL702257 | 0.79 | SETD1B (0.33) | — | |
| SCHEMBL708508 | 0.79 | UTS2R (0.32) | PIK3CAPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423204-A1 | THIAZOLIDINONE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2012-02-29 | — | — | EP | disclosed |