Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL705497 | 1.00 | PIK3CA (0.37) | PIK3CAPRKDCKDRPARP1LCK | |
| SCHEMBL703954 | 0.88 | PIK3CA (0.32) | PIK3CAPRKDCPARP1 | |
| SCHEMBL703955 | 0.88 | PIK3CA (0.32) | PIK3CAPRKDCPARP1 | |
| SCHEMBL708156 | 0.85 | PIK3CA (0.35) | PIK3CAPRKDCPARP1 | |
| SCHEMBL708159 | 0.85 | PIK3CA (0.35) | PIK3CAPRKDCPARP1 | |
| SCHEMBL708508 | 0.85 | UTS2R (0.32) | PIK3CAPRKDCLCKJAK3BTK | |
| SCHEMBL708157 | 0.84 | SYK (0.35) | PIK3CAPRKDCPARP1 | |
| SCHEMBL702258 | 0.83 | SETD1B (0.33) | — | |
| SCHEMBL702257 | 0.83 | SETD1B (0.33) | — | |
| SCHEMBL653422 | 0.78 | MAPT (0.39) | PIK3CAPRKDCKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423204-A1 | THIAZOLIDINONE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2012-02-29 | — | — | EP | disclosed |