Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12707568 | 1.00 | TDP1 (0.30) | TDP1TSHR | |
| SCHEMBL12707481 | 1.00 | TDP1 (0.30) | TDP1TSHR | |
| SCHEMBL18419251 | 0.97 | TSHR (0.32) | TDP1TSHR | |
| SCHEMBL5358136 | 0.97 | — | — | |
| SCHEMBL9843480 | 0.94 | CES2 (0.30) | TDP1TSHR | |
| SCHEMBL15003813 | 0.94 | CES2 (0.30) | TDP1TSHR | |
| SCHEMBL10981383 | 0.91 | UGT2B7 (0.31) | — | |
| SCHEMBL5326361 | 0.90 | — | — | |
| SCHEMBL16448668 | 0.90 | — | — | |
| SCHEMBL13980744 | 0.78 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205284-B1 | NOVEL METHOD FOR PREPARING NANOPARTICLES COVERED WITH A GEM-BISPHOSPHONATE STABILISING LAYER COUPLED TO HYDROPHILIC BIODISTRIBUTION LIGANDS | GUERBET SA (FR) | 2012-12-05 | — | — | EP | disclosed |
| EP-2409985-A2 | Inhibitors de serine proteases, especially of the NS3 protease of the hepatitis C virus | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-01-25 | — | — | EP | disclosed |
| EP-2314598-A1 | Inhibitors of Hepatitis C virus NS3 serine protease | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-04-27 | — | — | EP | disclosed |
| WO-2009053596-A2 | NOVEL METHOD FOR PREPARING NANOPARTICLES COVERED WITH A GEM-BISPHOSPHONATE STABILISING LAYER COUPLED TO HYDROPHILIC BIODISTRIBUTION LIGANDS | GUERBET (FR) | 2009-04-30 | — | — | WO | disclosed |
| US-20030183502-A1 | Process for purifying alicyclic alcohols | DRACHENFELSSEE 521. VV GMBH (TO BE RENAMED OXEA DEUTSCHLAND GMBH) (DE) | 2003-10-02 | — | — | US | disclosed |