Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 20/20 | 0.60 |
| ▸ | HTR2A | P28223 | 18/20 | 0.60 |
| ▸ | HTR2B | P41595 | 13/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7044303 | 0.84 | HTR2C (0.77) | HTR2CHTR2AHTR2BCYP1A2 | |
| SCHEMBL7039482 | 0.75 | HTR2C (1.00) | HTR2CHTR2AHTR2BCYP1A2 | |
| SCHEMBL8126904 | 0.74 | HTR2C (0.77) | HTR2CHTR2AHTR2BCYP1A2 | |
| SCHEMBL7079712 | 0.73 | HTR2C (0.77) | HTR2CHTR2AHTR2BCYP1A2 | |
| SCHEMBL8526280 | 0.70 | HTR2C (0.80) | HTR2CHTR2A | |
| SCHEMBL7040479 | 0.70 | HTR2C (0.75) | HTR2CHTR2AHTR2BCYP1A2 | |
| Hydrochloric Acid SCHEMBL7085794 | 0.69 | HTR2C (0.74) | HTR2CHTR2AHTR2BCYP1A2 | |
| SCHEMBL7042693 | 0.68 | HTR2C (1.00) | HTR2CHTR2AHTR2BCYP1A2 | |
| SCHEMBL8529186 | 0.68 | HTR2C (1.00) | HTR2CHTR2AHTR2B | |
| SCHEMBL8530118 | 0.68 | HTR2C (1.00) | HTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030105139-A1 | Indole derivatives as 5-HT receptor antagonist | SMITHKLINE BEECHAM P.L.C. | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105139-A1 | Indole derivatives as 5-HT receptor antagonist | HTR5A, HTR2C, HTR1A | HTR2C 2/4885HTR2A 4/4885HTR2B 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.