SCHEMBL7082199

SCHEMBL7082199

C=Cc1cc2ccc3ccc4cccc5c6cccc1c6c2c3c45

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.48
ERBB2 P04626 1/20 0.48
FYN P06241 1/20 0.48
MAOA P21397 1/20 0.48
ACHE P22303 1/20 0.48
AHR P35869 1/20 0.48
ALDH1A1 P00352 6/20 0.48
HSD17B10 Q99714 6/20 0.48
HPGD P15428 4/20 0.48
THRB P10828 1/20 0.48
TSHR P16473 4/20 0.36
CYP1B1 Q16678 3/20 0.36
CYP3A4 P08684 2/20 0.36
CYP1A1 P04798 2/20 0.36
TDP1 Q9NUW8 3/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
GUSB P08236 1/20 0.33
HIF1A Q16665 2/20 0.32
MAPK1 P28482 1/20 0.32
CASP1 P29466 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5271517 0.95 CYP1A2 (0.52) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL6560768 0.92 CYP1A2 (0.52) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL2199399 0.82 ESR1 (0.33) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL5271514 0.79 ALDH1A1 (0.48) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL1143168 0.77 ALDH1A1 (0.52) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL8722964 0.76 CYP1A2 (0.52) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL18171072 0.76 CYP1A2 (0.47) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL64873 0.76 ALDH1A1 (0.48) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL29438471 0.76 ALDH1A1 (0.48) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL17183979 0.76 ALDH1A1 (0.50) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0898562-B1 HYDROXAMIC ACID DERIVATIVES FOR USE WITH THE TREATMENT OF DISEASES RELATED TO CONNECTIVE TISSUE DEGRADATION UPJOHN CO (US) 2003-01-22 EP claimed
EP-0898562-B1 HYDROXAMIC ACID DERIVATIVES FOR USE WITH THE TREATMENT OF DISEASES RELATED TO CONNECTIVE TISSUE DEGRADATION UPJOHN CO (US) 2003-01-22 EP disclosed