Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14781423 | 0.86 | HTT (0.60) | HTTKDM4CALDH1A1HPGDLMNA | |
| SCHEMBL3030217 | 0.85 | HTT (0.44) | HTTKDM4CALDH1A1HPGDLMNA | |
| SCHEMBL3029473 | 0.84 | ATM (0.57) | HTTKDM4CALDH1A1HPGDLMNA | |
| SCHEMBL3020620 | 0.83 | HTT (0.43) | HTTKDM4CALDH1A1HPGDLMNA | |
| SCHEMBL1308720 | 0.83 | HTT (0.44) | HTTKDM4CALDH1A1HPGDLMNA | |
| SCHEMBL13843918 | 0.82 | MAPT (0.46) | HTTKDM4CALDH1A1HPGDLMNA | |
| SCHEMBL12918471 | 0.82 | NR3C1 (0.47) | HTTKDM4CALDH1A1HPGDLMNA | |
| SCHEMBL14266422 | 0.82 | HTT (0.42) | HTTKDM4CALDH1A1HPGDLMNA | |
| SCHEMBL11930691 | 0.82 | ALDH1A1 (0.57) | HTTALDH1A1HPGDLMNAATM | |
| SCHEMBL13843926 | 0.81 | HTT (0.41) | HTTKDM4CALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313709-A1 | PYRAZOLYL BIPHENYL CARBOXAMIDES | Bayer CropScience AG (DE) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002008195-A1 | PYRAZOLYL BIPHENYL CARBOXAMIDES AND THE USE THEREOF FOR CONTROLLING UNDESIRED MICROORGANISMS | BAYER CROPSCIENCE AG (DE) | 2002-01-31 | — | — | WO | disclosed |