Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUCY1B2 | O75343 | 6/20 | 0.36 |
| ▸ | GUCY1A2 | P33402 | 6/20 | 0.36 |
| ▸ | GUCY1A1 | Q02108 | 6/20 | 0.36 |
| ▸ | GUCY1B1 | Q02153 | 6/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | GPR6 | P46095 | 1/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10206667 | 0.93 | MEN1 (0.36) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1PPARG | |
| Trifluoroacetic Acid SCHEMBL712600 | 0.89 | FAAH (0.38) | SYK | |
| Trifluoroacetic Acid SCHEMBL709575 | 0.89 | SYK (0.34) | PPARGCASP3SENP8SENP6KDM4E | |
| Trifluoroacetic Acid SCHEMBL713293 | 0.88 | MEN1 (0.36) | PPARGCASP3SENP8SENP6KDM4E | |
| Trifluoroacetic Acid SCHEMBL711504 | 0.87 | NOS1 (0.35) | KDM4EMEN1KMT2ASYKGPR6 | |
| Trifluoroacetic Acid SCHEMBL709074 | 0.87 | NAMPT (0.36) | CASP3SENP8SENP6KDM4EMEN1 | |
| Trifluoroacetic Acid SCHEMBL718789 | 0.87 | PDE4A (0.35) | PPARGKDM4EMEN1KMT2ASYK | |
| Trifluoroacetic Acid SCHEMBL711518 | 0.86 | PDE4A (0.36) | HTT | |
| Trifluoroacetic Acid SCHEMBL712920 | 0.86 | KDM4E (0.38) | PPARGKDM4E | |
| Trifluoroacetic Acid SCHEMBL711889 | 0.86 | HDAC3 (0.34) | SYKSLC16A3SLC16A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940837-B1 | IMIDAZOPYRIDINE COMPOUNDS | TAKEDA PHARMACEUTICAL (JP) | 2012-11-07 | — | — | EP | disclosed |
| US-8124617-B2 | Imidazopyridine compounds | TAKEDA SAN DIEGO, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20100069431-A1 | IMIDAZOPYRIDINE COMPOUNDS | TAKEDA SAN DIEGO, INC. | 2010-03-18 | — | — | US | disclosed |
| EP-1940837-A2 | IMIDAZOPYRIDINE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007028135-A2 | IMIDAZOPYRIDINE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069431-A1 | IMIDAZOPYRIDINE COMPOUNDS | GCK, GCKR, KHK | GUCY1B2 1111/4885GUCY1A2 1185/4885GUCY1A1 1197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.