Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.56 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.56 |
| ▸ | ABAT | P80404 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8065690 | 0.85 | GPR35 (0.56) | ALDH1A1MAPK1HPGDTP53TSHR | |
| SCHEMBL8374513 | 0.85 | MAPK1 (0.60) | ALDH1A1MAPK1HPGDTP53TSHR | |
| Hydrochloric Acid SCHEMBL28214254 | 0.84 | GPR35 (0.55) | ALDH1A1MAPK1HPGDTP53TSHR | |
| SCHEMBL6881421 | 0.83 | HPGD (0.58) | ALDH1A1MAPK1HPGDTP53TSHR | |
| SCHEMBL27039902 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MAPK1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL18268223 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MAPK1HPGDTP53TSHR | |
| SCHEMBL3801985 | 0.81 | HTT (0.68) | ALDH1A1MAPK1HPGDTP53TSHR | |
| Hydrochloric Acid SCHEMBL29009198 | 0.80 | MAPK1 (0.58) | ALDH1A1MAPK1HPGDTP53TSHR | |
| SCHEMBL3378072 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPK1HPGDTP53TSHR | |
| SCHEMBL5499416 | 0.80 | CA12 (0.54) | ALDH1A1MAPK1HPGDTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575940-B1 | 2,4,6-TRISUBSTITUTED PYRIMIDINES AS PHOSPHOTIDYLINOSITOL (PI) 3-KINASE INHIBITORS AND THEIR USE IN THE TREATMENT OF CANCER | NOVARTIS AG (CH) | 2011-10-05 | — | — | EP | disclosed |
| EP-2316831-A1 | 2,4,6-trisubstituted pyrimidines as phosphotidylinositol (PI) 3-kinase inhibitors and their use in the treatment of cancer | Novartis AG (CH) | 2011-05-04 | — | — | EP | disclosed |
| US-7767669-B2 | Small molecule PI 3-kinase inhibitors and methods of their use | NOVARTIS AG (CH) | 2010-08-03 | — | — | US | disclosed |
| US-7767669-B2 | Small molecule PI 3-kinase inhibitors and methods of their use | NOVARTIS AG (CH) | 2010-08-03 | — | — | US | disclosed |
| US-20090060912-A1 | SMALL MOLECULE PI 3-KINASE INHIBITORS AND METHODS OF THEIR USE | CHIRON CORPORATION (US) | 2009-03-05 | — | — | US | disclosed |
| US-20090060912-A1 | SMALL MOLECULE PI 3-KINASE INHIBITORS AND METHODS OF THEIR USE | CHIRON CORPORATION (US) | 2009-03-05 | — | — | US | disclosed |
| US-7423148-B2 | Small molecule PI 3-kinase inhibitors and methods of their use | CHIRON CORPORATION (US) | 2008-09-09 | — | — | US | disclosed |
| US-7423148-B2 | Small molecule PI 3-kinase inhibitors and methods of their use | CHIRON CORPORATION (US) | 2008-09-09 | — | — | US | disclosed |
| EP-1324681-A2 | ARTICLE FOR THE DELIVERY OF FOAM PRODUCTS | THE PROCTER & GAMBLE COMPANY (US) | 2003-07-09 | — | — | EP | disclosed |
| US-6547063-B1 | Article for the delivery of foam products | THE PROCTER & GAMBLE COMPANY | 2003-04-15 | — | — | US | disclosed |
| EP-0706551-B1 | POLYALKYL HYDROXY AND AMINO AROMATIC CARBAMATES AND FUEL COMPOSITIONS CONTAINING THE SAME | CHEVRON CHEM CO (US) | 2000-06-07 | — | — | EP | disclosed |
| EP-0706554-A4 | POLY(OXYALKYLENE) HYDROXY AND AMINO AROMATIC CARBAMATES AND FUEL COMPOSITIONS CONTAINING THE SAME | CHEVRON CHEM CO (US) | 1996-09-18 | — | — | EP | disclosed |
| EP-0706551-A4 | POLYALKYL HYDROXY AND AMINO AROMATIC CARBAMATES AND FUEL COMPOSITIONS CONTAINING THE SAME | CHEVRON CHEM CO (US) | 1996-09-18 | — | — | EP | disclosed |
| EP-0706551-A1 | POLYALKYL HYDROXY AND AMINO AROMATIC CARBAMATES AND FUEL COMPOSITIONS CONTAINING THE SAME | CHEVRON CHEMICAL COMPANY (US) | 1996-04-17 | — | — | EP | disclosed |
| EP-0706554-A1 | POLY(OXYALKYLENE) HYDROXY AND AMINO AROMATIC CARBAMATES AND FUEL COMPOSITIONS CONTAINING THE SAME | CHEVRON CHEMICAL COMPANY (US) | 1996-04-17 | — | — | EP | disclosed |
| US-5484463-A | Poly(oxyalkylene) hydroxy and amino aromatic carbamates and fuel compositions containing the same | CHEVRON CHEMICAL COMPANY (US) | 1996-01-16 | — | — | US | disclosed |
| WO-1995029975-A1 | POLY(OXYALKYLENE) HYDROXY AND AMINO AROMATIC CARBAMATES AND FUEL COMPOSITIONS CONTAINING THE SAME | CHEVRON CHEMICAL COMPANY (US) | 1995-11-09 | — | — | WO | disclosed |
| WO-1995029972-A1 | POLYALKYL HYDROXY AND AMINO AROMATIC CARBAMATES AND FUEL COMPOSITIONS CONTAINING THE SAME | CHEVRON CHEMICAL COMPANY (US) | 1995-11-09 | — | — | WO | disclosed |
| US-5413615-A | Fuel additives, antideposit | CHEVRON CHEMICAL COMPANY (US) | 1995-05-09 | — | — | US | disclosed |
| US-3984405-A | PYRIDO(3,2-B)(1,4)OXAZIN-3(4H)-ONES | E. R. SQUIBB & SONS, INC. (US) | 1976-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090060912-A1 | SMALL MOLECULE PI 3-KINASE INHIBITORS AND METHODS OF THEIR USE | PI4KB, AKT3, PI4KA | ALDH1A1 4330/4885MAPK1 311/4885HPGD 2498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.