Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 5/20 | 0.62 |
| ▸ | ESR1 | P03372 | 10/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | STS | P08842 | 4/20 | 0.55 |
| ▸ | PGR | P06401 | 4/20 | 0.55 |
| ▸ | AR | P10275 | 4/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.55 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.55 |
| ▸ | SNCA | P37840 | 3/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | HTR2B | P41595 | 3/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6255112 | 0.84 | SHBG (0.59) | SHBGESR1ESR2HSD17B10LMNA | |
| SCHEMBL6260812 | 0.84 | SHBG (0.59) | SHBGESR1ESR2HSD17B10LMNA | |
| SCHEMBL11498773 | 0.82 | SHBG (0.46) | SHBGESR1ESR2HSD17B10LMNA | |
| SCHEMBL6633748 | 0.81 | STS (0.44) | SHBGESR1ESR2HSD17B10LMNA | |
| SCHEMBL6633753 | 0.81 | STS (0.44) | SHBGESR1ESR2HSD17B10LMNA | |
| SCHEMBL7082868 | 0.80 | STS (0.68) | ESR1ESR2STS | |
| SCHEMBL7082866 | 0.80 | STS (0.68) | ESR1ESR2STS | |
| SCHEMBL5675177 | 0.80 | ESR1 (0.64) | SHBGESR1ESR2HSD17B10LMNA | |
| SCHEMBL8778682 | 0.80 | ESR1 (0.64) | SHBGESR1ESR2HSD17B10LMNA | |
| SCHEMBL7147482 | 0.80 | ESR1 (0.64) | SHBGESR1ESR2HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030100544-A1 | Inhibiting tubulin polymerization; treating prostate and breast cancer | SCHERING AG (DE) | 2003-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100544-A1 | Inhibiting tubulin polymerization; treating prostate and breast cancer | TUBA1C, TUBB1, NR5A1 | SHBG 60/4885ESR1 328/4885ESR2 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.