Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594583 | 0.78 | ALDH1A1 (0.37) | ALDH1A1THRBMEN1KMT2AKDM4E | |
| SCHEMBL3716616 | 0.74 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL189533 | 0.71 | POLB (0.48) | ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL8604653 | 0.70 | KDM4E (0.32) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL418818 | 0.69 | KDM4E (0.35) | ALDH1A1KDM4EHPGD | |
| SCHEMBL8028307 | 0.69 | ALDH1A1 (0.33) | ALDH1A1KMT2A | |
| SCHEMBL1318679 | 0.69 | TSHR (0.37) | ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL3236537 | 0.68 | — | — | |
| SCHEMBL5491237 | 0.68 | KDM4E (0.31) | KDM4EHPGD | |
| SCHEMBL28810148 | 0.67 | CYP2C19 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057687-A1 | METHODS FOR PREPARING DOXORUBICIN DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2003-07-17 | — | — | WO | disclosed |