Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | PER2 | O15055 | 3/20 | 0.37 |
| ▸ | CRY1 | Q16526 | 3/20 | 0.37 |
| ▸ | CRY2 | Q49AN0 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7082835 | 0.88 | LMNA (0.43) | LMNAMEN1KMT2ATDP1CYP2D6 | |
| SCHEMBL7078271 | 0.85 | LMNA (0.44) | LMNAPOLBMEN1KMT2ATDP1 | |
| SCHEMBL7078282 | 0.82 | KMT2A (0.43) | POLBMEN1KMT2AGRM2CYP11B2 | |
| SCHEMBL7082113 | 0.79 | GRM2 (0.35) | LMNAGRM2CYP11B2 | |
| SCHEMBL5948078 | 0.78 | TDP1 (0.53) | POLBMEN1KMT2ATDP1PER2 | |
| SCHEMBL7078787 | 0.77 | PLA2G4A (0.39) | POLBMEN1KMT2AGRM2CYP11B2 | |
| SCHEMBL7077505 | 0.75 | ACKR3 (0.36) | LMNAGRM2TP53 | |
| SCHEMBL7077747 | 0.75 | ACKR3 (0.36) | POLBMEN1KMT2AGRM2BACE1 | |
| SCHEMBL14047589 | 0.73 | TDP1 (0.54) | POLBMEN1KMT2ATDP1PER2 | |
| SCHEMBL6480278 | 0.71 | FEN1 (0.46) | LMNAPOLBMEN1KMT2AGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030229079-A1 | 1-(Aromatic- or heteroaromatic-substituted)-3-(heteroaromatic substituted)-1,3-propanediones and uses thereof | PAYNE LINDA S (US) | 2003-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229079-A1 | 1-(Aromatic- or heteroaromatic-substituted)-3-(heteroaromatic substituted)-1,3-propanediones and uses thereof | CYP2S1, IMPDH1, IDO1 | LMNA 3637/4885POLB 24/4885MEN1 4377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.