SCHEMBL7083043

SCHEMBL7083043

CC(Oc1ccc(Oc2cnc3cc(Cl)ccc3n2)cc1)C(=O)Cl

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.72
CYP1A2 P05177 3/20 0.72
MAPT P10636 3/20 0.72
LMNA P02545 3/20 0.72
HPGD P15428 2/20 0.72
NPSR1 Q6W5P4 2/20 0.72
CYP3A4 P08684 2/20 0.72
SMN1; SMN2 Q16637 2/20 0.72
TP53 P04637 1/20 0.72
ALOX15 P16050 1/20 0.72
NFKB1 P19838 1/20 0.72
HIF1A Q16665 1/20 0.72
GMNN O75496 1/20 0.72
APEX1 P27695 1/20 0.72
PMP22 Q01453 1/20 0.72
HTT P42858 8/20 0.50
L3MBTL1 Q9Y468 4/20 0.50
CYP2C19 P33261 2/20 0.44
CYP2C9 P11712 1/20 0.44
RAB9A P51151 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31186228 1.00 ALDH1A1 (0.72) ALDH1A1CYP1A2MAPTLMNAHPGD
SCHEMBL28344338 1.00 ALDH1A1 (0.72) ALDH1A1CYP1A2MAPTLMNAHPGD
Quizalofop SCHEMBL1010164 0.91 ALDH1A1 (0.72) ALDH1A1CYP1A2MAPTLMNAHPGD
Quizalofop SCHEMBL29763487 0.91 ALDH1A1 (0.72) ALDH1A1CYP1A2MAPTLMNAHPGD
Quizalofop SCHEMBL19210826 0.91 ALDH1A1 (0.72) ALDH1A1CYP1A2MAPTLMNAHPGD
Quizalofop SCHEMBL111413 0.91 ALDH1A1 (0.72) ALDH1A1CYP1A2MAPTLMNAHPGD
SCHEMBL13316454 0.91 ALDH1A1 (0.72) ALDH1A1CYP1A2MAPTLMNAHPGD
Quizalofop SCHEMBL63325 0.91 ALDH1A1 (0.72) ALDH1A1CYP1A2MAPTLMNAHPGD
Quizalofop SCHEMBL10942454 0.90 ALDH1A1 (0.71) ALDH1A1CYP1A2MAPTLMNAHPGD
Quizalofop SCHEMBL10978823 0.89 ALDH1A1 (0.92) ALDH1A1CYP1A2MAPTLMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107382980-B N- [ (dihydrobenzofuran-7-oxy) alkyl ] -2-aryloxyamide derivatives 湖南大学 2020-05-15 CN disclosed
CN-107176950-B Aryloxy phenoxy propionate compound and preparation method and application thereof 赣州市正畅塑胶有限公司 2019-12-31 CN disclosed
EP-0912528-B1 PROCESSES FOR PRODUCING PHENOXY PROPIONIC ACID DERIVATIVES NISSAN CHEMICAL IND LTD (JP) 2003-05-28 EP disclosed
US-6136977-A Processes for producing phenoxy propionic acid derivatives NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2000-10-24 US disclosed
EP-0580932-A1 Herbicidal quinoxalinyloxy ethers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-02-02 EP disclosed
US-5250690-A Selective killing of grassy weeds DOWELANCO (US) 1993-10-05 US disclosed
WO-1993003020-A1 HERBICIDAL QUINOXALINYLOXY ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-02-18 WO disclosed
EP-0527016-A1 Herbicidal quinoxalinyloxy ethers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-02-10 EP disclosed
US-4968343-A GRASSY WEEDS IN PRESENCE OF CORN PLANTS THE DOW CHEMICAL COMPANY (US) 1990-11-06 US disclosed
EP-0121871-B1 PROPIONIC-ACID ESTERS AND THEIR USE IN COMBATING WEEDS F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1988-01-20 EP disclosed
US-4687849-A [(Isopropylideneamino)oxy]-ethyl-2-[[6-chloroquinoxalinyl)oxy]phenoxy]propionate postemergent herbicide HOFFMANN-LA ROCHE INC. (US) 1987-08-18 US disclosed
EP-0205821-A1 Haloalkoxy anilide derivatives of 2-(4-heterocyclic oxyphenoxy)-alkanoic acids and their use as herbicides THE DOW CHEMICAL COMPANY (US) 1986-12-30 EP disclosed
EP-0082699-B1 HERBICIDAL QUINOXALINYL ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-11-13 EP disclosed
US-4522647-A Substituted phenoxyalkanediones and their herbicidal method of use ZOECON CORPORATION (US) 1985-06-11 US disclosed
EP-0023785-B1 QUINOXALINYLOXYPHENOXYALKANE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES ICI AUSTRALIA LIMITED (AU) 1985-04-03 EP disclosed
US-4500737-A Compositions ZOECON CORPORATION (US) 1985-02-19 US disclosed
EP-0109483-A1 Substituted phenoxyalkane diones, intermediates for these compounds and the use of phenoxyalkane diones in the control of weeds ZOECON CORPORATION (US) 1984-05-30 EP disclosed
US-4448965-A Substituted cycloalkanediones ZOECON CORPORATION (US) 1984-05-15 US disclosed
EP-0082699-A1 Herbicidal quinoxalinyl ethers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-06-29 EP disclosed
EP-0023785-A2 Quinoxalinyloxyphenoxyalkane carboxylic acid derivatives, their preparation and their use as herbicides ICI AUSTRALIA LIMITED (AU) 1981-02-11 EP disclosed