Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7076391 | 0.86 | REN (0.56) | REN | |
| SCHEMBL6960392 | 0.84 | REN (0.54) | REN | |
| SCHEMBL6041585 | 0.83 | REN (0.54) | REN | |
| SCHEMBL7080632 | 0.82 | REN (0.50) | REN | |
| SCHEMBL6041274 | 0.81 | RAB9A (0.35) | REN | |
| SCHEMBL7566402 | 0.81 | REN (0.51) | REN | |
| Tert-Butyl Formate SCHEMBL27502532 | 0.76 | REN (0.48) | REN | |
| SCHEMBL6041250 | 0.74 | REN (0.56) | REN | |
| Trifluoroacetic Acid SCHEMBL7136875 | 0.72 | REN (0.53) | REN | |
| SCHEMBL7079897 | 0.71 | REN (0.53) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |
| US-6150526-A | Piperidine derivative having renin inhibiting activity | HOFFMANN-LA ROCHE INC. (US) | 2000-11-21 | — | — | US | disclosed |