Sugi Predict

Sugi Predict / Compounds / SCHEMBL286112

SCHEMBL286112

SCHEMBL286112

CCOC(=O)C=CN(C)C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HCAR2 Q8TDS4 2/20 0.56
▸ MAPT P10636 3/20 0.46
▸ NPSR1 Q6W5P4 1/20 0.43
▸ CA12 O43570 1/20 0.43
▸ CA1 P00915 1/20 0.43
▸ CA2 P00918 1/20 0.43
▸ CA7 P43166 1/20 0.43
▸ CA9 Q16790 1/20 0.43
▸ CA14 Q9ULX7 1/20 0.43
▸ ALOX15 P16050 1/20 0.42
▸ ALDH1A1 P00352 3/20 0.41
▸ TDP1 Q9NUW8 1/20 0.40
▸ ATM Q13315 1/20 0.40
▸ CYP2C9 P11712 1/20 0.40
▸ TTR P02766 1/20 0.40
▸ DPP4 P27487 1/20 0.40
▸ LMNA P02545 2/20 0.39
▸ HSD17B10 Q99714 1/20 0.39
▸ MDM2 Q00987 1/20 0.38
▸ KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8354202 1.00 HCAR2 (0.56) HCAR2MAPTNPSR1CA12CA1
SCHEMBL286141 1.00 HCAR2 (0.56) HCAR2MAPTNPSR1CA12CA1
SCHEMBL28347745 0.87 HCAR2 (0.44) HCAR2MAPTNPSR1CA12CA1
SCHEMBL29159477 0.87 HCAR2 (0.44) HCAR2MAPTNPSR1CA12CA1
SCHEMBL21126304 0.84 ATM (0.46) HCAR2MAPTNPSR1ALDH1A1TDP1
SCHEMBL1171459 0.83 HCAR2 (0.59) HCAR2MAPTNPSR1ALDH1A1TDP1
SCHEMBL7083152 0.83 HCAR2 (0.59) HCAR2MAPTNPSR1ALDH1A1TDP1
SCHEMBL22897008 0.83 HCAR2 (0.52) HCAR2MAPTNPSR1CA12CA1
Hydrochloric Acid SCHEMBL8108663 0.81 HCAR2 (0.57) HCAR2MAPTNPSR1ALDH1A1TDP1
SCHEMBL1871206 0.80 HCAR2 (0.54) HCAR2MAPTNPSR1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 723 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111296-A1 ELECTROLYTE COMPOSITIONS AND ELECTROCHEMICAL DEVICES USING THE SAME II-VI DELAWARE, INC. (US) 2025-05-30 — — WO claimed
US-20240416332-A1 POSITIVELY CHARGED QUATERNARY AMMONIUM SALT POLYMER CATALYST AND PREPARATION METHOD AND APPLICATION THEREOF UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA (CN) 2024-12-19 — — US claimed
CN-118515614-A Synthesis method of difluoro pyrazole acid 南京大学 2024-08-20 — — CN claimed
CN-117966518-B Pressure-resistant anti-deformation corrugated board and preparation process thereof 东莞市益和纸制品有限公司 2024-07-09 — — CN claimed
CN-115504448-B Preparation method of phosphorus pentafluoride carbonate complex and co-production of sodium hexafluorophosphate 山东中顼技术研究有限公司 2024-06-21 — — CN claimed
CN-114195715-B Process for preparing 1-methyl-3-difluoromethyl-4-pyrazole acid and 1-methyl-3-trifluoromethyl-4-pyrazole acid 福建永晶科技股份有限公司 2024-05-10 — — CN claimed
CN-117966518-A Pressure-resistant anti-deformation corrugated board and preparation process thereof 东莞市益和纸制品有限公司 2024-05-03 — — CN claimed
CN-117623857-A Purification method of electronic grade octafluoro-2-butene 浙江省化工研究院有限公司 2024-03-01 — — CN claimed
CN-117623855-A Method for absorbing and purifying octafluoro-2-butene 浙江省化工研究院有限公司 2024-03-01 — — CN claimed
CN-117623858-A Extractive distillation method of octafluoro-2-butene 浙江省化工研究院有限公司 2024-03-01 — — CN claimed
US-20100274049-A1 Method for the production of 2-fluoroacyl-3-aminoacrylic acid derivatives BAYER CROPSCIENCE AG (DE) 2010-10-28 — — US claimed
US-20100204483-A1 PROCESS FOR PREPARING 2-DIHALOACYL-3-AMINOACRYLIC ACID DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-08-12 — — US claimed
EP-2195284-A1 PROCESS FOR PREPARING 2-DIHALOACYL-3-AMINOACRYLIC ACID DERIVATIVES Bayer CropScience AG (DE) 2010-06-16 — — EP claimed
WO-2009083134-A1 METHOD FOR THE PRODUCTION OF 2-FLUOROACYL-3-AMINO-ACRYLIC ACID DERIVATIVES BAYER CROPSCIENCE AG (DE) 2009-07-09 — — WO claimed
EP-2072497-A1 Method for manufacturing 2-fluoracyl-3-amino-acrylic acid derivatives Bayer CropScience AG (DE) 2009-06-24 — — EP claimed
WO-2009043444-A1 PROCESS FOR PREPARING 2-DIHALOACYL-3-AMINOACRYLIC ACID DERIVATIVES BAYER CROPSCIENCE AG (DE) 2009-04-09 — — WO claimed
EP-2042482-A1 Method for manufacturing 2-dihalogenacyl-3-amino-acrylic acid derivatives Bayer CropScience AG (DE) 2009-04-01 — — EP claimed
EP-0176846-B1 3-AMINO-2-BENZOYL-ACRYLIC-ACID DERIVATIVES AND PROCESS FOR THEIR PREPARATION BAYER AG (DE) 1989-08-16 — — EP claimed
CN-85101686-B 3-amino-2-benzoyl-acrylic acid derivative and a process for producing the same 拜尔公司 1988-12-14 — — CN claimed
EP-0176846-A2 3-Amino-2-benzoyl-acrylic-acid derivatives and process for their preparation BAYER AG (DE) 1986-04-09 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204483-A1 PROCESS FOR PREPARING 2-DIHALOACYL-3-AMINOACRYLIC ACID DERIVATIVES AADAT, DDC, IDUA HCAR2 590/4885MAPT 3232/4885NPSR1 2213/4885
US-20100274049-A1 Method for the production of 2-fluoroacyl-3-aminoacrylic acid derivatives AADAT, AADAC, ALAD HCAR2 264/4885MAPT 3643/4885NPSR1 2981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.