Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 13/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6054814 | 0.83 | CACNA1B (0.40) | CACNA1BNR1I2MEN1KMT2APTGDR2 | |
| SCHEMBL8495216 | 0.83 | CFTR (0.38) | CACNA1BNR1I2MEN1KMT2APTGDR2 | |
| SCHEMBL6054858 | 0.83 | CACNA1B (0.39) | CACNA1BNR1I2MEN1KMT2APTGDR2 | |
| SCHEMBL6599147 | 0.79 | NPC1 (0.34) | MEN1KMT2A | |
| SCHEMBL6054776 | 0.79 | MLYCD (0.38) | CACNA1BNR1I2PTGDR2 | |
| Isoxaflutole SCHEMBL29355326 | 0.79 | DHODH (0.48) | CACNA1BNR1I2CYP3A4MEN1KMT2A | |
| Isoxaflutole SCHEMBL66989 | 0.79 | DHODH (0.48) | CACNA1BNR1I2CYP3A4MEN1KMT2A | |
| Isoxaflutole SCHEMBL21645075 | 0.79 | DHODH (0.48) | CACNA1BNR1I2CYP3A4MEN1KMT2A | |
| Isoxaflutole SCHEMBL20723459 | 0.78 | DHODH (0.47) | CACNA1BNR1I2CYP3A4MEN1KMT2A | |
| Isoxaflutole SCHEMBL20723475 | 0.78 | DHODH (0.47) | CACNA1BNR1I2CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066270-B1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-07-30 | — | — | EP | disclosed |
| US-6255251-B1 | CONTROLLING WEEDS | SYNGENTA CROP PROTECTION, INC. | 2001-07-03 | — | — | US | disclosed |
| EP-1066270-A1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | Novartis AG (CH) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999051583-A1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | NOVARTIS AG (CH) | 1999-10-14 | — | — | WO | disclosed |