Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.31 |
| ▸ | FASN | P49327 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.30 |
| ▸ | GPR6 | P46095 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599094 | 0.85 | NPC1 (0.36) | NPC1HTTPTGS2KMT2ACCNE1 | |
| SCHEMBL6600395 | 0.82 | NPC1 (0.34) | NPC1HTTPTGS2CCNE1CDK2 | |
| SCHEMBL7083430 | 0.79 | CACNA1B (0.40) | MEN1KMT2A | |
| SCHEMBL8490493 | 0.79 | ALDH1A1 (0.36) | HTTPTGS2POLB | |
| SCHEMBL6429850 | 0.77 | LMNA (0.36) | NPC1RAB9A | |
| SCHEMBL8683983 | 0.77 | DHODH (0.36) | NPC1KMT2ACCNE1CDK2KIF18A | |
| SCHEMBL6594174 | 0.73 | NPC1 (0.40) | NPC1MEN1KMT2AGPR6RAB9A | |
| SCHEMBL8763742 | 0.72 | NR1H4 (0.36) | NPC1KIF18A | |
| SCHEMBL8762509 | 0.72 | LMNA (0.34) | NPC1PTGS2KIF18A | |
| SCHEMBL8492339 | 0.72 | NPC1 (0.39) | NPC1MEN1KMT2AGPR6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901479-B1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-02-11 | — | — | EP | claimed |
| US-6297198-B1 | COMPOUNDS WITH SULFUR GROUPS ON ISOXAZOLE RINGS AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-10-02 | — | — | US | claimed |
| EP-0901479-A1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | Novartis AG (CH) | 1999-03-17 | — | — | EP | claimed |
| WO-1997043270-A1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | NOVARTIS AG (CH) | 1997-11-20 | — | — | WO | claimed |
| EP-0901479-B1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-02-11 | — | — | EP | disclosed |
| US-6297198-B1 | COMPOUNDS WITH SULFUR GROUPS ON ISOXAZOLE RINGS AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-10-02 | — | — | US | disclosed |
| EP-0901479-A1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | Novartis AG (CH) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997043270-A1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | NOVARTIS AG (CH) | 1997-11-20 | — | — | WO | disclosed |