SCHEMBL708380

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1285053	0.93	LPAR1 (0.44)	LPAR1PPARGNPSR1KDM4EPOLB
	SCHEMBL709120	0.83	POLB (0.49)	NPSR1KDM4EPOLBHDAC1ALDH1A1
	SCHEMBL707130	0.82	PPARG (0.54)	LPAR1PPARGKDM4EPOLB
	SCHEMBL706447	0.75	LPAR1 (0.52)	LPAR1PPARGKDM4EPOLBALDH1A1
	SCHEMBL708371	0.75	POLB (0.54)	KDM4EPOLBALDH1A1
	SCHEMBL707824	0.73	LPAR1 (0.52)	LPAR1PPARGAGTR1AGTR2
	SCHEMBL707714	0.71	LPAR1 (0.51)	LPAR1PPARGNPSR1KDM4EPOLB
	SCHEMBL1617954	0.69	ERN1 (0.64)	LPAR1KDM4EALDH1A1
	SCHEMBL709347	0.69	LPAR1 (0.78)	LPAR1
	SCHEMBL704971	0.69	PPARG (0.48)	LPAR1PPARGKDM4EPOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.