SCHEMBL706447

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL707824	0.93	LPAR1 (0.52)	LPAR1PPARGAGTR1AGTR2BRS3
	SCHEMBL707717	0.86	SLC6A2 (0.47)	LPAR1PPARGKMT2AKDM4E
	SCHEMBL707130	0.83	PPARG (0.54)	LPAR1PPARGPOLBKDM4E
	SCHEMBL705825	0.82	SRD5A2 (0.57)	POLBMEN1KMT2AKDM4EALDH1A1
	SCHEMBL709317	0.81	MCL1 (0.47)	PPARGPOLBMEN1KMT2AKDM4E
	SCHEMBL708944	0.79	LPAR1 (0.52)	LPAR1PPARGPOLBCCR2MEN1
	SCHEMBL706891	0.77	KMT2A (0.42)	POLBCCR2MEN1KMT2AKDM4E
	SCHEMBL709318	0.77	PLA2G4A (0.45)	POLBMEN1KMT2AKDM4EALDH1A1
	SCHEMBL708380	0.75	LPAR1 (0.51)	LPAR1PPARGAGTR1AGTR2POLB
	SCHEMBL708371	0.71	POLB (0.54)	POLBMEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.