SCHEMBL708387

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL709246	0.83	TDP1 (0.60)	LMNASMN1; SMN2HTTTDP1L3MBTL1
	SCHEMBL8816104	0.83	KMT2A (0.56)	LMNASMN1; SMN2HTTTDP1L3MBTL1
	SCHEMBL969334	0.82	TDP1 (0.59)	LMNASMN1; SMN2HTTTDP1L3MBTL1
	Hydrochloric Acid SCHEMBL8812982	0.82	KMT2A (0.55)	LMNASMN1; SMN2HTTTDP1L3MBTL1
	SCHEMBL7823257	0.80	ALDH1A1 (0.61)	LMNASMN1; SMN2HTTTDP1L3MBTL1
	SCHEMBL8548671	0.79	LMNA (0.51)	LMNASMN1; SMN2HTTTDP1L3MBTL1
	SCHEMBL8549825	0.79	HPGD (0.61)	LMNASMN1; SMN2HTTTDP1L3MBTL1
	Hydrochloric Acid SCHEMBL8548328	0.78	HPGD (0.60)	LMNASMN1; SMN2HTTTDP1L3MBTL1
	SCHEMBL3859999	0.77	TDP1 (0.61)	SMN1; SMN2HTTTDP1L3MBTL1KMT2A
	SCHEMBL7046987	0.77	ALDH1A1 (0.72)	SMN1; SMN2TDP1L3MBTL1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.