Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983848 | 0.86 | GNRHR (0.57) | GNRHR | |
| SCHEMBL6982756 | 0.80 | HDAC1 (0.41) | GNRHR | |
| SCHEMBL6984830 | 0.79 | GNRHR (0.43) | GNRHR | |
| SCHEMBL7084004 | 0.74 | GNRHR (0.43) | GNRHR | |
| SCHEMBL6978088 | 0.68 | POLB (0.53) | GNRHR | |
| SCHEMBL8698046 | 0.62 | GNRHR (0.54) | GNRHR | |
| SCHEMBL7912503 | 0.59 | GNRHR (0.72) | GNRHR | |
| SCHEMBL8002899 | 0.59 | GNRHR (1.00) | GNRHR | |
| SCHEMBL7605067 | 0.58 | ALDH1A1 (0.50) | — | |
| SCHEMBL7995735 | 0.57 | GNRHR (0.84) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095038-B1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO INC (US) | 2003-09-03 | — | — | EP | disclosed |
| EP-0873336-B1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO INC (US) | 2002-03-27 | — | — | EP | disclosed |
| US-6200957-B1 | USEFUL FOR TREATMENT OF VARIETY OF SEX-HORMONE RELATED AND OTHER CONDITIONS IN BOTH MEN AND WOMEN | MERCK & CO., INC. | 2001-03-13 | — | — | US | disclosed |