Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 3/20 | 0.41 |
| ▸ | GABRD | O14764 | 3/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.41 |
| ▸ | GABRE | P78334 | 3/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11119468 | 0.85 | GABRA5 (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27167090 | 0.79 | HTT (0.43) | HTTACHEKMT2ABCHECA2 | |
| SCHEMBL15542709 | 0.79 | HTT (0.61) | HTTACHEKMT2ALMNAALDH1A1 | |
| SCHEMBL4477003 | 0.79 | ALDH1A1 (0.41) | HTTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2555883 | 0.77 | HTT (0.41) | HTTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11349002 | 0.75 | — | — | |
| SCHEMBL76429 | 0.75 | MAOB (0.43) | HTT | |
| SCHEMBL77616 | 0.74 | HTT (0.48) | HTTACHEBCHECA2SMN1; SMN2 | |
| SCHEMBL18989524 | 0.73 | CYP2C9 (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL18989817 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003104984-A | METHOD FOR PRODUCING SUBSTITUTED AMINOPYRIMIDINYLACETAMIDE DERIVATIVE | NIPPON KAYAKU CO LTD | 2003-04-09 | — | — | JP | disclosed |