Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.41 |
| ▸ | PLAU | P00749 | 3/20 | 0.41 |
| ▸ | PLAT | P00750 | 3/20 | 0.41 |
| ▸ | PLG | P00747 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6793205 | 0.89 | PTGS1 (0.47) | MCHR1PTGS1KDM4ETRPV1 | |
| SCHEMBL7083682 | 0.89 | CA12 (0.45) | CA12CA1CA2CA9MCHR1 | |
| SCHEMBL7080710 | 0.88 | SORT1 (0.43) | CA12CA1CA2CA9MCHR1 | |
| SCHEMBL7084075 | 0.87 | CA12 (0.43) | CA12CA1CA2CA9MCHR1 | |
| SCHEMBL7084422 | 0.85 | ITGB1 (0.44) | CA12CA1CA2CA9PTGS1 | |
| SCHEMBL7083646 | 0.79 | GAA (0.49) | MAPTNPC1RAB9AKIT | |
| SCHEMBL6489566 | 0.79 | GCGR (0.43) | MCHR1PTGS1TRPV1IL2KIT | |
| SCHEMBL6492769 | 0.79 | P2RX1 (0.50) | MCHR1PTGS1KDM4EMAPTPPARG | |
| SCHEMBL6799011 | 0.79 | PTGS1 (0.47) | MCHR1PTGS1MAPTTRPV1 | |
| SCHEMBL6791861 | 0.78 | PTGS1 (0.51) | PTGS1TRPV1KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |