Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795248 | 0.90 | SMO (0.47) | GAAHTR2CHTR2AHTR2BRAB9A | |
| SCHEMBL6259089 | 0.83 | GAA (0.53) | GAALRRK2RAB9ASRPK3NPC1 | |
| SCHEMBL7083682 | 0.82 | CA12 (0.45) | RAB9ANPC1MAPT | |
| SCHEMBL7084422 | 0.82 | ITGB1 (0.44) | GAALRRK2KDRNTRK1 | |
| SCHEMBL7084075 | 0.82 | CA12 (0.43) | LRRK2MAPT | |
| SCHEMBL6499436 | 0.81 | RAB9A (0.46) | GAAHTR2CHTR2AHTR2BRAB9A | |
| SCHEMBL7086871 | 0.81 | HTR2C (0.49) | GAAHTR2CHTR2AHTR2BLRRK2 | |
| SCHEMBL6793010 | 0.79 | HTR2C (0.50) | GAAHTR2CHTR2AHTR2BRAB9A | |
| SCHEMBL7084151 | 0.79 | CA12 (0.43) | RAB9AKITNPC1MAPT | |
| SCHEMBL6924381 | 0.78 | GAA (0.45) | GAAHTR2CHTR2AHTR2BLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |