Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 18/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7085297 | 0.90 | SERPINE1 (0.81) | SERPINE1LMNA | |
| SCHEMBL7087883 | 0.82 | SERPINE1 (0.69) | SERPINE1 | |
| SCHEMBL7089125 | 0.78 | SERPINE1 (1.00) | SERPINE1 | |
| SCHEMBL7088324 | 0.78 | SERPINE1 (1.00) | SERPINE1 | |
| SCHEMBL7088252 | 0.76 | SERPINE1 (0.77) | SERPINE1KDM4EALDH1A1GAA | |
| SCHEMBL1421137 | 0.76 | SERPINE1 (1.00) | SERPINE1 | |
| SCHEMBL7084542 | 0.73 | SERPINE1 (1.00) | SERPINE1 | |
| SCHEMBL7091010 | 0.71 | SERPINE1 (1.00) | SERPINE1 | |
| SCHEMBL7089570 | 0.70 | SERPINE1 (0.61) | SERPINE1LMNATSHRHTT | |
| SCHEMBL7088443 | 0.70 | SERPINE1 (0.90) | SERPINE1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080060-A1 | SUBSTITUTED PIPERAZINE ANTITHROMBOTIC PAI-1 INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | WO | disclosed |