Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978671 | 0.92 | F2 (0.46) | F2ALDH1A1PARP1NR3C1RORC | |
| SCHEMBL6981981 | 0.92 | F2 (0.40) | F2ALDH1A1PARP1NR3C1RORC | |
| Hydrochloric Acid SCHEMBL7086319 | 0.87 | F10 (0.42) | F2ALDH1A1PARP1NR3C1RORC | |
| SCHEMBL7084264 | 0.86 | F2 (0.40) | F2PARP1F10F7ITGB3 | |
| SCHEMBL7956920 | 0.85 | F2 (0.46) | F2ALDH1A1PARP1NR3C1RORC | |
| Hydrochloric Acid SCHEMBL6979622 | 0.85 | F2 (0.39) | F2ALDH1A1PARP1NR3C1RORC | |
| Hydrochloric Acid SCHEMBL7958487 | 0.85 | NR3C1 (0.38) | F2ALDH1A1PARP1NR3C1F10 | |
| Hydrochloric Acid SCHEMBL6980680 | 0.84 | PARP1 (0.39) | F2ALDH1A1PARP1NR3C1F10 | |
| Hydrochloric Acid SCHEMBL6984704 | 0.82 | NR3C1 (0.49) | ALDH1A1NR3C1POLBGAA | |
| SCHEMBL6976662 | 0.82 | F2 (0.60) | F2ALDH1A1NR3C1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |