Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 4/20 | 0.35 |
| ▸ | F7 | P08709 | 2/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978680 | 0.92 | KEAP1 (0.47) | F2ITGB3ITGA2BKEAP1NFE2L2 | |
| SCHEMBL7084262 | 0.86 | F2 (0.46) | F2ITGB3ITGA2BF10F7 | |
| SCHEMBL6979635 | 0.81 | ITGB3 (0.40) | F2ITGB3ITGA2BKEAP1NFE2L2 | |
| SCHEMBL6982999 | 0.80 | ALDH1A1 (0.41) | F2ITGB3ITGA2BPLGPRSS1 | |
| SCHEMBL6978671 | 0.79 | F2 (0.46) | F2ITGB3ITGA2BKEAP1NFE2L2 | |
| SCHEMBL6976368 | 0.79 | ITGB3 (0.39) | F2ITGB3ITGA2BF10F7 | |
| SCHEMBL6985790 | 0.79 | KEAP1 (0.46) | F2ITGB3ITGA2BKEAP1NFE2L2 | |
| SCHEMBL6985025 | 0.79 | F7 (0.42) | F2ITGB3ITGA2BF10F7 | |
| SCHEMBL6981981 | 0.78 | F2 (0.40) | F2F10F7PLGPRSS1 | |
| SCHEMBL6981750 | 0.77 | AVPR2 (0.38) | F2ITGB3ITGA2BKEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |