Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601329 | 0.91 | ALDH1A1 (0.34) | ALDH1A1TSHRCREBBPCYP2C19CYP2D6 | |
| SCHEMBL5698005 | 0.91 | ALDH1A1 (0.34) | ALDH1A1TSHRCREBBPCYP2C19CYP2D6 | |
| SCHEMBL534176 | 0.89 | ALDH1A1 (0.31) | ALDH1A1TSHRCREBBPCYP2C19CYP2D6 | |
| SCHEMBL29817538 | 0.89 | ALDH1A1 (0.31) | ALDH1A1TSHRCREBBPCYP2C19CYP2D6 | |
| SCHEMBL30384808 | 0.87 | MEN1 (0.34) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL14874589 | 0.87 | MEN1 (0.34) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL4758984 | 0.80 | TSHR (0.42) | ALDH1A1TSHRLMNAHTTGAA | |
| SCHEMBL27895655 | 0.79 | TSHR (0.41) | ALDH1A1TSHRCYP2D6CYP1A2LMNA | |
| SCHEMBL11703874 | 0.78 | TSHR (0.40) | ALDH1A1TSHRLMNAHTTGAA | |
| SCHEMBL10385058 | 0.77 | KDM4E (0.44) | ALDH1A1TSHRCREBBPCYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811368-B1 | DENTAL PRIMER COMPOSITION AND POLYMERIZATION CATALYST | TOKUYAMA CORP (JP) | 2003-07-23 | — | — | EP | disclosed |
| EP-0811368-A1 | DENTAL PRIMER COMPOSITION AND POLYMERIZATION CATALYST | TOKUYAMA CORPORATION (JP) | 1997-12-10 | — | — | EP | disclosed |