Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MYOC | Q99972 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2072071 | 0.77 | MAPT (0.67) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL6487654 | 0.76 | MAPT (0.46) | MEN1KMT2ARAB9AMAPTGAA | |
| SCHEMBL28915066 | 0.75 | MEN1 (0.68) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL6678960 | 0.74 | MGLL (0.56) | KMT2ANPC1RAB9AMAPTGAA | |
| SCHEMBL12916012 | 0.74 | MAPT (0.62) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL27182807 | 0.73 | MAPT (0.61) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL23541512 | 0.72 | MAPT (0.60) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL10944355 | 0.72 | MAPT (0.80) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL4238027 | 0.72 | MAPT (0.61) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL2071222 | 0.71 | KMT2A (0.63) | MEN1KMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |