Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 6/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7079008 | 0.91 | REN (0.42) | RENSLC6A3SLC6A4 | |
| SCHEMBL7081269 | 0.89 | REN (0.47) | RENSLC6A3SLC6A4 | |
| SCHEMBL7082510 | 0.86 | REN (0.49) | REN | |
| SCHEMBL7081090 | 0.86 | REN (0.38) | RENSLC6A3SLC6A4 | |
| SCHEMBL6041973 | 0.85 | REN (0.41) | RENSLC6A3SLC6A4 | |
| SCHEMBL7078125 | 0.84 | REN (0.38) | RENSLC6A3SLC6A4 | |
| SCHEMBL7078204 | 0.80 | REN (0.46) | REN | |
| SCHEMBL7566649 | 0.79 | REN (0.43) | RENSLC6A3SLC6A4 | |
| SCHEMBL7082332 | 0.78 | SLC6A4 (0.39) | SLC6A3SLC6A4 | |
| SCHEMBL7566629 | 0.77 | SLC6A4 (0.40) | RENSLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |