Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7084710 | 0.86 | SMN1; SMN2 (0.40) | HSP90AA1ALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL6964074 | 0.82 | HSP90AA1 (0.42) | HSP90AA1ALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL7084637 | 0.81 | MAOA (0.35) | ALDH1A1HPGD | |
| SCHEMBL7084513 | 0.81 | LMNA (0.39) | ALDH1A1LMNAHPGD | |
| SCHEMBL6973535 | 0.81 | HSP90AA1 (0.41) | HSP90AA1ALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL7079831 | 0.81 | HSP90AA1 (0.41) | HSP90AA1ALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL6968750 | 0.81 | PDE4A (0.39) | HSP90AA1ALDH1A1LMNAHPGDPOLB | |
| SCHEMBL6973949 | 0.81 | MAPT (0.39) | ALDH1A1LMNASMN1; SMN2HPGDPOLB | |
| SCHEMBL7084665 | 0.77 | KMT2A (0.40) | HSP90AA1ALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL6966066 | 0.76 | HSP90AA1 (0.36) | HSP90AA1ALDH1A1LMNASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |