SCHEMBL7084800

SCHEMBL7084800

CC(C)(c1ccccc1)c1ccc(O)c(C(=O)O)c1.[Zn]

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.52
ESR2 Q92731 3/20 0.52
ALDH1A1 P00352 3/20 0.52
CYP3A4 P08684 2/20 0.52
HNF4A P41235 4/20 0.50
ACMSD Q8TDX5 3/20 0.50
MCL1 Q07820 3/20 0.50
DHFR P00374 1/20 0.50
CSNK2A1 P68400 1/20 0.49
CNR1 P21554 2/20 0.48
CNR2 P34972 2/20 0.48
CA1 P00915 3/20 0.47
CA2 P00918 3/20 0.47
CA12 O43570 2/20 0.47
CA7 P43166 2/20 0.47
CA9 Q16790 2/20 0.47
CA14 Q9ULX7 2/20 0.47
PTGS2 P35354 2/20 0.47
ALOX5 P09917 1/20 0.47
PTPN1 P18031 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5442998 0.98 ESR1 (0.53) ESR1ESR2ALDH1A1CYP3A4HNF4A
SCHEMBL10464291 0.93 CSNK2A1 (0.55) ESR1ESR2ALDH1A1CYP3A4HNF4A
SCHEMBL10464421 0.92 ESR1 (0.55) ESR1ESR2ALDH1A1CYP3A4HNF4A
SCHEMBL9244550 0.91 CSNK2A1 (0.57) ESR1ALDH1A1CYP3A4HNF4AACMSD
SCHEMBL11756691 0.90 ACMSD (0.61) ESR1ESR2HNF4AACMSDMCL1
SCHEMBL7090681 0.90 ACMSD (0.60) HNF4AACMSDMCL1DHFRCNR1
SCHEMBL9769847 0.88 ACMSD (0.63) ESR1ESR2HNF4AACMSDMCL1
SCHEMBL95477 0.88 CA1 (0.58) ESR1ESR2ALDH1A1CYP3A4HNF4A
SCHEMBL313199 0.88 ACMSD (0.62) ESR1ESR2HNF4AACMSDMCL1
SCHEMBL11753853 0.87 CA1 (0.53) ESR1ESR2ALDH1A1CYP3A4HNF4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030191023-A1 Thermosensitive recording material FUJI PHOTO FILM CO., LTD. 2003-10-09 US claimed
JP-58205797-A None JP disclosed
JP-56112955-A None JP disclosed
JP-S58205797-A HEAT-SENSITIVE RECORDING MATERIAL RICOH CO LTD 1983-11-30 JP disclosed
JP-S56112955-A HALOGEN-CONTAINING RESIN COMPOSITION SUMITOMO CHEM CO LTD 1981-09-05 JP disclosed