SCHEMBL9769847

SCHEMBL9769847

CC(C)(c1ccccc1)c1ccc(-c2cccc(C(C)(C)c3ccc(O)c(C(=O)O)c3)c2)cc1

nearest known ligand 0.63

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACMSD Q8TDX5 7/20 0.63
MCL1 Q07820 7/20 0.62
HNF4A P41235 2/20 0.62
DHFR P00374 1/20 0.62
RXRA P19793 1/20 0.51
RXRB P28702 1/20 0.51
CNR1 P21554 2/20 0.50
CNR2 P34972 2/20 0.50
GSTA1 P08263 1/20 0.47
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11756691 0.99 ACMSD (0.61) ACMSDMCL1HNF4ADHFRRXRA
SCHEMBL313199 0.97 ACMSD (0.62) ACMSDMCL1HNF4ADHFRRXRA
SCHEMBL7090681 0.96 ACMSD (0.60) ACMSDMCL1HNF4ADHFRRXRA
SCHEMBL11776527 0.96 ACMSD (0.60) ACMSDMCL1HNF4ADHFRRXRA
SCHEMBL5697819 0.94 ACMSD (0.67) ACMSDMCL1HNF4ADHFRRXRA
SCHEMBL5442998 0.90 ESR1 (0.53) ACMSDMCL1HNF4ADHFRCNR1
SCHEMBL7084800 0.88 ESR1 (0.52) ACMSDMCL1HNF4ADHFRCNR1
SCHEMBL10464421 0.87 ESR1 (0.55) ACMSDMCL1HNF4ADHFRCNR1
SCHEMBL10464291 0.85 CSNK2A1 (0.55) ACMSDMCL1HNF4ADHFRESR1
SCHEMBL9244550 0.83 CSNK2A1 (0.57) ACMSDMCL1HNF4ADHFRESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5017546-A Metallized phenolic resins SCHENECTADY INTERNATIONAL, INC. 1991-05-21 US disclosed
US-4999333-A For facsimile and thermal printing FUJI PHOTO FILM CO., LTD. (JP) 1991-03-12 US disclosed
US-4134847-A HOMOGENIZING AN AROMATIC CARBOXYLIC ACID-POLYMER-METAL CARBONATE OR OXIDE MELT KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1979-01-16 US disclosed