Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29661383 | 0.79 | KMT2A (0.54) | LMNAHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22814704 | 0.76 | MEN1 (0.45) | AKR1C3AKR1C1LMNASTAT3HTT | |
| SCHEMBL31254284 | 0.76 | KMT2A (0.58) | AKR1C3AKR1C1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3496093 | 0.76 | KMT2A (0.58) | AKR1C3AKR1C1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6296187 | 0.76 | MEN1 (0.51) | AKR1C3AKR1C1LMNASTAT3HTT | |
| SCHEMBL19272351 | 0.76 | NLRP3 (0.58) | — | |
| SCHEMBL13585121 | 0.76 | MEN1 (0.49) | AKR1C3AKR1C1LMNASTAT3HTT | |
| SCHEMBL13585118 | 0.76 | MEN1 (0.49) | AKR1C3AKR1C1LMNASTAT3HTT | |
| SCHEMBL6827755 | 0.75 | KMT2A (0.57) | AKR1C3AKR1C1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13690284 | 0.74 | LMNA (0.48) | AKR1C3AKR1C1LMNASTAT3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592439-B1 | AMINOSULFONYL CARBAMATES | WARNER LAMBERT CO (US) | 2003-07-30 | — | — | EP | disclosed |